Inhibition by L-Threonine of Aspartokinase as a Cause of Threonine Toxicity to Methylococcus capsulatus
نویسندگان
چکیده
منابع مشابه
Enzymatic Breakdown of Threonine by Threonine Aldolase
1. The enzyme which splits threonine to acetaldehyde and glycine has been partially purified from rat liver (five- to sixfold purification) and the name threonine aldolase proposed for it. 2. The general properties of threonine aldolase have been studied. The enzyme is unstable to a pH below 5. The pH optimum of the enzyme reaction is at 7.5-7.7. The initial rate of production of acetaldehyde i...
متن کاملNucleotide sequence of the Serratia marcescens threonine operon and analysis of the threonine operon mutations which alter feedback inhibition of both aspartokinase I and homoserine dehydrogenase I.
The nucleotide sequence of the Serratia marcescens threonine operon (thrA1A2BC) was determined. Three long open reading frames were identified; these open reading frames code for aspartokinase I (AKI)-homoserine dehydrogenase I (HDI), homoserine kinase, and threonine synthase, in that order. The predicted amino acid sequences of these enzymes were similar to the amino acid sequences of the corr...
متن کاملProperties of threonine deaminase from a bacterium able to use threonine as sole source of carbon.
A threonine deaminase susceptible to inhibition by isoleucine was purified over 3,000-fold from extracts of Pseudomonas multivorans, a bacterium able to use threonine or alpha-ketobutyrate as sole source of carbon and energy. The enzyme was characterized with respect to molecular weight, dissociation to subunits, and apparent affinities for threonine, isoleucine, and several other ligands. Cert...
متن کاملtranslating allusive devices:a survey of a portrait of the artist as a young man by james joyce
تلمیح یکی از عناصری است که تقریباً در همه ی متون ادبی یافت و باعث ایجاد شکاف های فرهنگی می شود. در این تحقیق به عنوان شکلی از بینامتنیت در ترجمه مورد توجه قرار می گیرد. تلاش شده است تا راهکارهای مترجمان برای ترجمه چهار نوع اسامی خاص و عبارات کلیدی تلمیحی (مذهبی، سیاسی، تاریخی و اسطوره ای) موجود در رمانِ چهره مرد هنرمند در جوانی به فارسی بررسی شود. این تحقیق مقایسه ای بر اساس راهکارهای ترجمه تلمیح...
15 صفحه اولRat liver L-threonine dehydrogenase.
L-threonine dehydrogenase (E.C.1.1.1.103) catalyzes the NAD+-dependent transformation of Lthreonine to 2-amino 3-0x0-butyric acid, which spontaneously loses CO2 with the final production of aminoacetone ( 1) The enzyme is present in several microorganisms as well as in the liver of vertebrates (2-6). We studied some properties of the rat liver enzyme, showing that the activity was strongly inhi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of General Microbiology
سال: 1973
ISSN: 0022-1287
DOI: 10.1099/00221287-75-1-223